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Fibroblast Growth Factor-23, Human Recombinant

Catalog #: 228-11892

Product Description

Specifications

Size20 µg, 1000 µg
Estimated Lead Time2-3 weeks
SpeciesHuman
Accession Number
Q9GZV9
Gene Id
8074
Protein Name / Synonyms
Tumor-derived hypophosphatemia-inducing factor, HYPF, ADHR, HPDR2, PHPTC, FGF23, FGF-23, Fibroblast Growth Factor-23.
Expressed Region
MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI.
Expression SystemE. coli
Purity
Greater than 95.0% as determined by SDS-PAGE.
Format
Sterile Filtered white lyophilized powder.
Formulation
The FGF-23 protein (0.5mg/ml) was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Activity
The biological activity of FGF-23 was measured in a cell proliferation assay using NIH/3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.05-0.5 ug/ml in the presence of 5 ug/ml of Recombinant Mouse Klotho and 10 ug/ml of heparin.
Research AreaCardiovascular Disease, Cancer
Shipping TypeAmbient temperature
Storage-20°C

Description

Description

Fibroblast Growth Factor-23 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing a total of 228 amino acids and having a molecular mass of 22.5kDa. The FGF-23 is and purified by chromatographic techniques.

Stability & Storage

Storage/Stability
Lyophilized FGF-23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-23 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.