Introduction
Cell death occurs through multiple regulated pathways in response to cellular stress, including oxidative stress, metabolic disruption, infection, and immune activation. Dysregulation of these programs contributes to cancer, neurodegenerative disorders, autoimmune disease, and infectious disease, creating a need for tools that broadly profile cell-death-associated gene expression.
Product Features
- SYBR Green-based qPCR array for simultaneous expression profiling
- 90 rigorously validated, highly specific primer pairs
- Includes six controls: three reference genes (INC) for normalization, a genomic DNA control (GDC), a positive PCR control (PC), and a negative control (NC)
- Simple workflow — just add cDNA and qPCR master mix
- High-quality results in as little as two hours
Array Content
Simultaneous profiling of 90 validated regulators across 12 cell death pathways — apoptosis, necroptosis, pyroptosis, ferroptosis, parthanatos, alkaliptosis, oxeiptosis, autophagy-dependent cell death (ADCD), NETosis, anoikis, disulfidptosis, and cuproptosis — plus six on-plate controls.
Format Selection / Instrument Key
Select the array plate format that matches your real-time PCR instrument:
- Plate A: ABI 5700, ABI 7000, ABI 7300, ABI 7500, ABI 7700
- Plate B: ABI 7500 Fast, ABI 7900 HT Fast, ABI StepOnePlus, ABI ViiA 7 Fast, Bio-Rad CFX Connect
- Plate C: Roche LightCycler 96, Roche LightCycler 480 (96-well)
Kit Components
- 96-Well Array Plate(s), preloaded with validated paired primers (2 µL/well)
- 2X qPCR Master Mix with Hot Start Taq
- 96-Well Plate Sealing Film
Storage/Stability
Store the kit at -20°C for up to 12 months prior to opening. Avoid repeated freeze-thaw cycles.
Product Use
For research use only. Not for use in clinical or in vitro diagnostic procedures.
