This AKT3 monoclonal antibody is generated from mouse immunized with AKT3 recombinant protein.
Clonality
Monoclonal
Species
Human, Mouse
Introduction
AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Specificity
Other Names
AKT3; PKBG; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; RAC-PK-gamma; STK-2
NCBI Accession #
NP_001193658.1;NP_005456.1;NP_859029.1
Other Accession #
Q9WUA6; NP_859029.1
Format
Type
Purified Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
55775
Recommended Dilutions
WB: 1:100-500; IHC: 1:50-100
AKT3 (Cat# 102-10072) western blot analysis in mouse NIH-3T3 cell line lysates (15ug/lane).This demonstrates the AKT3 antibody detected the AKT3 protein (arrow).
AKT3 Monoclonal Antibody (Cat# 102-10072) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AKT3 Monoclonal Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
