Mouse Anti-Bi-Phospho-MET/HGFR(Y1234/Y1235) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Accession Number | P08581 |
| Gene Id | 4233 |
| Gene Symbols | MET |
| Protein Name / Synonyms | Bi-Phospho-MET/HGFR(Y1234/Y1235) |
| Clonality | Monoclonal |
| Preparation | This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Tyr1234/1235 region of human Met and residues both Tyr1234 and Tyr1235 are phosphorylated. |
| Concentration (lot specific) | 0.450 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
MET; Hepatocyte growth factor receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; Tyrosine-protein kinase Met
NCBI Accession #
NP_000236.2;NP_001120972.1
Format
Type
Purified Phospho-specific Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
155541
Recommended Dilutions
WB: 1:100-500
 | Detection of endogenous Met in HepG2 cell line. 10 ug/lane of HepG2 cell lysate was used to examine the expression of human Met. Lanes 1-5 represent RayBiotech's different anti-Met monoclonal antibodies that are Cat# 102-10002 through 102-10006. Lane 6 represents auto-phosohorylated-Met in HepG2 cell line detected by anti-phospho-Met Mab (Cat# 102-10001). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.