Protein Name & Synonyms:
Immunohistology - Frozen, ELISA, Flow Cytometry, Western Blotting
DANGER - this product contains DISODIUM TETRABORATE DECAHYDRATE, BORIC ACID. May damage fertility. May damage the unborn child.
This product recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b❏'s alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonisation and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kDa) and alpha 3 (25 kDa) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
DANGER - HARMFUL IF SWALLOWED. - This product contains DISODIUM TETRABORATE DECAHYDRATE, BORIC ACID. May damage fertility. May damage the unborn child.
Purified IgG - liquid
Borate buffered saline
Purified human C4c
||Sodium Azide (NaN3)