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Antigen Information
Protein Name & Synonyms:
Cba
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, ELISA, Flow Cytometry, Functional Assays, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
Specificity
This product recognizes the 30kDa Ba fragment of 90kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Borate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Purified human complement factor b
Preservative:
0.1% Sodium Azide (NaN3)
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
