Protein Name & Synonyms:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
IgG concentration 1 mg/ml
Human, This product reacts with Cynomolgus monkey, rhesus monkey and baboon tissues Does not cross react with feline tissues
This product recognizes the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.
This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Rheumatoid synovial cells and human monocytes
Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.