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Antigen Information
Protein Name & Synonyms:
CD11b4
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1 ml distilled water
Species Reactivity:
Human, Cynomolgus monkey, Rhesus monkey and Baboon tissues Does not cross react with feline tissues
Specificity
This product recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes.
The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.
This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.
This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
Storage/Stability
Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1 ml distilled water
Preparation
Immunogen:
Rheumatoid Synovial cells and Human Monocytes
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
| 5% | Sucrose |
This product
Spleen cells from immunised BALB/c mice were fused with cells of the SP2 mouse myeloma cell line.
No posts found
Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
