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Antigen Information
Protein Name & Synonyms:
CD146
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, ELISA (dilution: 1/10 , 1/50), Flow Cytometry
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Pig
Specificity
This product recognizes the 118kD cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells.
CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.
CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Recombinant human MUC18 (D1-D5) Fc protein.
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
