Protein Name & Synonyms:
CD146
Applications:
Immunohistology - Frozen, ELISA (dilution: 1/10 , 1/50), Flow Cytometry
Concentration (lot specific):
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Pig
This product recognizes the 118kD cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells.
CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Recombinant human MUC18 (D1-D5) Fc protein.
This product
Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.