Protein Name & Synonyms:
Flow Cytometry, Immunoprecipitation
IgG concentration 1.0 mg/ml
This product recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen).
This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail.
Both molecules are members of the newly described natural killer cell receptor family.
CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
NK cell This product class='ty-product-feature'>
0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.