Mouse Anti-Human CD158b

Mouse Anti-Human CD158b (0.2 mg)

$571.00
DS-MB-00382
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Antigen Information

Protein Name & Synonyms:
CD158b
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human

Specificity

This product recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen).

This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail.

Both molecules are members of the newly described natural killer cell receptor family.

CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
NK cell This product class='ty-product-feature'>
Preservative:
0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.