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Antigen Information
Protein Name & Synonyms:
CD16
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunohistology - Paraffin
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Human
Specificity
This product recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. This antibody recognizes all polymorphonuclear cells irrespective on their NA phenotype.
Studies show that the antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Studies show that the antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
CD34 antigen
Preservative:
| 0.09% | Sodium Azide (NaN3) |
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
