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Antigen Information
Protein Name & Synonyms:
CD284
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry, Immunoprecipitation, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Rhesus monkey and guinea pig
Specificity
This product recognizes the human Toll like receptor 4 (TLR4) cell surface antigen.
TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.
TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Ba/F3 cell line expressing TLR4 (CD284)
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
