Protein Name & Synonyms:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
IgG concentration 1.0 mg/ml
Human, chicken Does not cross react with porcine, lapine or bovine tissue
This product recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. This product reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Osteoclasts from osteoclastomas
Spleen cells from immunised mice were fused with cells of the mouse X63.Ag8.653 myeloma cell line.