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Antigen Information
Protein Name & Synonyms:
CD51/CD61
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, chicken Does not cross react with porcine, lapine or bovine tissue
Specificity
This product recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. This product reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Osteoclasts from osteoclastomas
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised mice were fused with cells of the mouse X63.Ag8.653 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
