Mouse Anti-Human CD86

Mouse Anti-Human CD86 (25 ug)


Product Specifications

25 µg

Protein Information

Protein Name & Synonyms:
Target Species:
  • Human

Antibody Specifications

Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration (lot specific):
IgG concentration 1.0 mg/ml


Mouse anti Human CD86 antibody recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co - stimulaory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an Ig -v -like domain which contains the CTLA -4 binding site and an adjacent C2-like domain. CD86 plays an important role in co - stimulation of T cell proliferation , IL-2 production and in the primary immune response.

Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, clone Bu63 is located within the Ig -v -like domain of human CD86.

Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells.


Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.


Supplied as:
Purified IgG - liquid
TRIS buffered saline
Format Type:


Human peripheral blood lymphocytes.
0.09%Sodium Azide
This product
Spleen cells from immunised mice were fused with cells of the P3 X63 Ag8.653 myeloma cell line.
12 months from the date of shipment when stored properly.

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This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.