Purified His-tagged CDH1 protein was used to produced this monoclonal antibody.
Clonality
Monoclonal
Species
Human
Introduction
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
CDH1 Antibody(Cat# 102-10403) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the CDH1 antibody detected the CDH1 protein (arrow).
Antigen Source
Human
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
