This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.
Clonality
Monoclonal
Species
Human
Introduction
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
CDKN1C Antibody (Cat# 102-10303) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CDKN1C antibody detected the CDKN1C protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.