This DISC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from human DISC1.
Clonality
Monoclonal
Species
Human
Introduction
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Specificity
Other Names
DISC1; KIAA0457; Disrupted in schizophrenia 1 protein
DISC1 Antibody(Cat# 102-10335) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DISC1 antibody detected the DISC1 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.