This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.
The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.