Mouse Anti-Human IL1B (Center) (Ascites) Antibody, 0.1 ml
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Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P01584 |
| Gene Id | 3553 |
| Gene Symbols | IL1B |
| Protein Name / Synonyms | IL1B (Center) (Ascites) |
| Clonality | Monoclonal |
| Preparation | This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B. |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].
Specificity
Predicted Reactivity
Monkey, Rabbit
Other Names
IL1B; IL1F2; Interleukin-1 beta; Catabolin
NCBI Accession #
NP_000567.1
Other Accession #
P14628; P79182; NP_000567.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
30748
Recommended Dilutions
WB: 1:2000-4000
 | IL1B Antibody (Center)(Ascites)(Cat# 102-10345). 293 cell lysates transiently transfected with the IL1B gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.