This RYK monoclonal antibody is generated from mouse immunized with RYK recombinant protein.
Clonality
Monoclonal
Species
Human
Introduction
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. Two alternative splice variants have been identified, encoding distinct isoforms.
Specificity
Other Names
RYK; JTK5A; Tyrosine-protein kinase RYK
NCBI Accession #
NP_001005861.1;NP_002949.2
Other Accession #
NP_001005861.1; NP_002949.2
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
67507
Recommended Dilutions
WB: 1:100-500
RYK (Cat# 102-10146) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the RYK antibody detected the RYK protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
