This STC2 monoclonal antibody is generated from mouse immunized with STC2 recombinant protein.
Clonality
Monoclonal
Species
Human
Introduction
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Specificity
Other Names
STC2; Stanniocalcin-2; Stanniocalcin-related protein
NCBI Accession #
NP_003705.1
Other Accession #
NP_003705.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
33249
Recommended Dilutions
WB: 1:100-250
STC2 Antibody (Cat# 102-10190) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the STC2 antibody detected the STC2 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
