Mouse Anti-KDM5C / Jarid1C / SMCX Antibody, 100 µl
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Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P41229 |
| Gene Id | 8242 |
| Gene Symbols | KDM5C |
| Protein Name / Synonyms | DXS1272E;Histone demethylase JARID1C;JARID1C;JmjC domain containing protein SMCX;Jumonji AT rich interactive domain 1C;Jumonji, AT rich interactive domain 1C (RBP2 lik |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting, ICC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot detection of KDM5C / Jarid1C / SMCX in Hela and 293 cell lysates using KDM5C / Jarid1C / SMCX mouse mAb (1:1000 diluted).Predicted band size: 176KDa.Observed band size: 220KDa.
ICC (1:150)
Immunocytochemistry of HeLa cells using anti-KDM5C / Jarid1C / SMCX mouse mAb diluted 1:150.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.