This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
Clonality
Monoclonal
Species
Human, Mouse, Rat
Introduction
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
PCNA Antibody (C-term) (Cat# 102-10464) western blot analysis in Hela,mouse L929 and rat C6 cell line lysates (35ug/lane).This demonstrates the PCNA antibody detected the PCNA protein (arrow).
Antigen Source
Human
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
