Protein Name & Synonyms:
CD54
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
This product recognizes the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a 90kD adhesion molecule belonging to the immunoglobulin superfamily.
CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and is known to play an important role in various cell-cell interactions in the immune system. Recent studies suggest that cross-linking of ICAM-1 using This product induces calcium signalling, see Etienne, S. et al. for details.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Rat Ax cells (a HEV derived cell line)
This product
Spleen cells from immunised BALB/c mice were fused with cells from the PAI mouse myeloma cell line.