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ISO 13485:2016 cGMP
Native CYTOMEGALOVIRUS
Catalog #: 229-20252
Product Description
Specifications
| Size | 1 mL |
| Estimated Lead Time | 1-2 weeks |
| Protein Name / Synonyms | CYTOMEGALOVIRUS, |
| Expression System | Cytomegalovirus strain AD-169, cultured in MRC-5, a diploid cell line of human lung origin. |
| Format | Inactivated Cytomegalovirus - liquid |
| Concentration (lot specific) | Total protein concentration ~3.2 mg/ml |
| Preservative | None present |
| Recommended Applications | ELISA |
| Shipping Type | Dry ice (additional shipping fee) |
| Storage | -70°C |
Description
Introduction
Cytomegalovirus is a member of the Herpesviridae family. It may be transmitted from person to person through urine, saliva, other bodily fluids, breast milk and transplanted organs. It is a common infection which mostly passes unnoticed. The infection may be dangerous to people who are immunocompromised such as those who are HIV positive or organ transplant recipients. The infection may also be dangerous to pre- and post-natal infants. Antiviral drugs are useful in the treatment of CMV infection.
MRC-5 monolayers are infected in a manner which will ensure that the full host of viral proteins are present upon harvest. Optimally infected tissue is collected in glycine buffered saline. The cells are disrupted to release cellular CMV antigen. Cellular debris is removed by centrifugation.
The antigen preparation is inactivated using gamma radiation, which primarily damages viral genetic material.
The antigen preparation is inactivated using gamma radiation, which primarily damages viral genetic material.
Specifications
Size
1 ml
Assay Buffers
Glycine buffered saline
Instructions for Use
129-20252 should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of immunoassay formats or may be further purified to meet the requirements of a particular assay format.
Inactivation
This product has been rendered inactive by standard procedures. However this material should still be handled as infectious and should be disposed of appropriately.
Stability & Storage
Storage/Stability
Store at -70°C.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. This protein may be stored for18 months from date of dispatch.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. This protein may be stored for18 months from date of dispatch.