Rabbit Anti-AAK1 (C-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q2M2I8|Q3UHJ0|P0C1X8|F1SPM8|F1MH24 |
| Gene Id | 22848 |
| Gene Symbols | AAK1 |
| Protein Name / Synonyms | AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048 |
| Clonality | Polyclonal |
| Clone | RB16779 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Other Information
NCBI Accession #
NP_055726.3
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
103885
Antigen Source
Human
Images
WB (1:1000)
Western blot analysis of anti-AAK1 Antibody (C-term) (Cat.#102-27418) in HepG2 cell line lysates (35ug/lane). AAK1 (arrow) was detected using the purified Pab.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.