Rabbit Anti-Bi-Phospho-GSK3B(S21/29) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P49841 |
| Gene Id | 2932 |
| Gene Symbols | GSK3B |
| Protein Name / Synonyms | Bi-Phospho-GSK3B(S21/29) |
| Clonality | Polyclonal |
| Preparation | This GSK3B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S21/29 of human GSK3B. |
| Concentration (lot specific) | 0.450 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.
Specificity
Other Names
GSK3B; Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B
NCBI Accession #
NP_001139628.1;NP_002084.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46744
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-Phospho-GSK3B-S21/29 Pab (Cat# 102-15303) is used in Western blot to detect Phospho-GSK3B-S21/29 in mouse thymus tissue lysate. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.