This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
Host Species
Rabbit
Clonality
Polyclonal
Species
Human, Mouse
Introduction
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
Specificity
Other Names
CASC4; Protein CASC4; Cancer susceptibility candidate gene 4 protein
CASC4 Antibody (C-term) (Cat# 102-10682) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).
CASC4 Antibody (C-term) (Cat# 102-10682) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
