CD127 pAb
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P16871 |
| Gene Id | 3575 |
| Gene Symbols | IL7R |
| Protein Name / Synonyms | IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, interleukin 7 receptor |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IF |
| Research Area | Inflammation, Autoimmune Disease, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Dilutions
WB 1:500 - 1:2000; IF 1:20 - 1:50
Format
Calculated MW
28kDa/29kDa/34kDa/51kDa
Observed MW
75kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CD127 (NP_002176.2).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.