Rabbit Anti-Human CAMKK2 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96RR4 |
| Gene Id | 10645 |
| Gene Symbols | CAMKK2 |
| Protein Name / Synonyms | CAMKK2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
CAMKK2; CAMKKB; KIAA0787; Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase kinase beta
NCBI Accession #
NP_001257414.1;NP_001257415.1;NP_006540.3;NP_705719.2;NP_705720.1;NP_757363.1;NP_757364.1;NP_757365.1;NP_757380.1
Other Accession #
O88831; Q8C078
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
64746
Recommended Dilutions
WB: 1:1000; IHC: 1:50
 | Western blot analysis of CAMKK2 (arrow) using rabbit polyclonal CAMKK2 Antibody (C-term)(Cat# 102-17138). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMKK2 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMKK2 antibody (C-term)(Cat#AP711b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.