Rabbit Anti-Human CDC14B (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O60729 |
| Gene Id | 8555 |
| Gene Symbols | CDC14B |
| Protein Name / Synonyms | CDC14B (Center) |
| Clonality | Polyclonal |
| Preparation | This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Specificity
Predicted Reactivity
Mouse
Other Names
CDC14B; Dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B
NCBI Accession #
NP_001070649.1;NP_003662.1;NP_201588.1
Other Accession #
A4D256; Q6PFY9
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56802
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of CDC14B Antibody (Center) (Cat# 102-18136) in 293 cell line lysates (35ug/lane). CDC14B (arrow) was detected using the purified Pab. |
 | CDC14B Antibody (Center) (Cat# 102-18136) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.