This Histone H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human Histone H3.
Host Species
Rabbit
Clonality
Polyclonal
Species
Human
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein targeted by this antibody is a replication-independent member of the histone H3 family.
Western blot analysis of Histone H3 (N-term) (Cat# 102-10686) in HL60 cell line lysates (35ug/lane). Histone H3 (arrow) was detected using the purified Pab.
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
