Rabbit Anti-Human ITPKB (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P27987 |
| Gene Id | 3707 |
| Gene Symbols | ITPKB |
| Protein Name / Synonyms | ITPKB (N-term) |
| Clonality | Polyclonal |
| Preparation | This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Research Area | Akt Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Specificity
Other Names
ITPKB; Inositol-trisphosphate 3-kinase B; Inositol 1,4,5-trisphosphate 3-kinase B
NCBI Accession #
NP_002212.3
Other Accession #
NP_002212
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
102376
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of ITPKB (arrow) using rabbit polyclonal ITPKB Antibody (R38) (Cat# 102-17845). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITPKB gene. |
 | ITPKB Antibody (N-term) (Cat# 102-17845)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITPKB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | ITPKB Antibody (N-term) (Cat# 102-17845) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.