Rabbit Anti-Human Phospho-MUC1(T1224) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P15941 |
| Gene Id | 4582 |
| Gene Symbols | MUC1 |
| Protein Name / Synonyms | Phospho-MUC1(T1224) |
| Clonality | Polyclonal |
| Preparation | This MUC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1224 of human MUC1. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Dot Blotting, IF |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
MUC1 is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Specificity
Other Names
MUC1; PUM; Mucin-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; PEMT; Peanut-reactive urinary mucin; Polymorphic epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin; CD_antigen=CD227; Mucin-1 subunit alpha; Mucin-1 subunit beta; MUC1-CT
NCBI Accession #
NP_001018016.1;NP_001018017.1;NP_001037855.1;NP_001037856.1;NP_001037857.1;NP_001037858.1;NP_001191214.1;NP_001191215.1;NP_001191216.1;NP_001191217.1;NP_001191218.1;NP_001191219.1;NP_001191220.1;NP_00
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
122102
Recommended Dilutions
DB: 1:500; IF: 1:10-50
 | Dot blot analysis of anti-Phospho-MUC1-pT1224 Phospho-specific Pab (Cat# 102-15535) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
 | Confocal immunofluorescent analysis of Phospho-MUC1-T1224 Antibody(Cat# 102-15535) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.