Rabbit Anti-Human PLN (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P26678 |
| Gene Id | 5350 |
| Gene Symbols | PLN |
| Protein Name / Synonyms | PLN (N-term) |
| Clonality | Polyclonal |
| Preparation | This PLN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-22 amino acids from the N-terminal region of human PLN. |
| Concentration (lot specific) | 0.390 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig, Rabbit
Other Names
Cardiac phospholamban, PLB, PLN, PLB
Other Accession #
P61016; P61015; P61013; P61014; A4IFH6
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
6109
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of lysate from U266 cell line,using PLN Antibody (N-term)(Cat# 102-14904).102-14904 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.