Rabbit Anti-Human TAP1 (C-term)

Rabbit Anti-Human TAP1 (C-term)

$462.00
DS-PB-02757
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Antigen Information

Protein Name & Synonyms:
TAP1
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: , 1/1000), Flow Cytometry, Immunoprecipitation, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Preparation:
Antisera to TAP1 (C-terminal) were raised by repeated immunisations of rabbits with highly purified antigen.
Species Reactivity:
Human

This product detects a band of approximately 72kDa

Specificity

This product detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an 81kDa membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex.

TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.

This product does not cross react with TAP2.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Antisera to TAP1 (C-terminal) were raised by repeated immunisations of rabbits with highly purified antigen.

Immunogen:
TAP1 peptide corresponding to the C-terminal of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Preservative:
0.01%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.