This ZNF197 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the N-terminal region of human ZNF197.
Host Species
Rabbit
Clonality
Polyclonal
Species
Human
Introduction
ZNF197 product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. ZNF197 is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.
Specificity
Other Names
ZNF197; ZKSCAN9; ZNF166; Zinc finger protein 197; Zinc finger protein with KRAB and SCAN domains 9; ZnF20; pVHL-associated KRAB domain-containing protein
ZNF197 Antibody (N-term) (Cat# 102-10693) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ZNF197 antibody detected the ZNF197 protein (arrow).
ZNF197 antibody (N-term) (Cat# 102-10693) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZNF197 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
