Rabbit Anti-NIK (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Rat |
| Host Species | Rabbit |
| Accession Number | Q99558 |
| Gene Id | 9020 |
| Gene Symbols | MAP3K14 |
| Protein Name / Synonyms | NIK (Center) |
| Clonality | Polyclonal |
| Preparation | This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Specificity
Other Names
MAP3K14; NIK; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK
NCBI Accession #
NP_003945.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
104042
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-NIK Pab (Cat# 102-17733) is used in Western blot to detect NIK in 293 cell lysate (Lane 1) and rat testis tissue lysate (Lane 2). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.