This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.

WB 1:500 - 1:2000; IHC 1:50 - 1:200

Recombinant fusion protein containing a sequence corresponding to amino acids 24-148 of human NTS (NP_006174.1).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.