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Ultrasensitive Biomarker Testing Service

1,000 Times More Sensitive Than ELISA

Single molecule array (Simoa™) testing is a powerful new technique that is orders of magnitude more sensitive than standard sandwich based immunoassay techniques. Traditional ELISA measurements are limited to pg/ml levels of detection. The RayBio Ultrasensitive Simoa Testing Services can achieve sensitivity as low as femtogram (fg/ml) levels, allowing the detection and quantification of biomarkers at concentrations previously difficult or impossible to measure.

Available Assays

RayBiotech is currently offering the below ultrasensitive assays for immediate testing:

Amyloid beta 1-40
BDNF
BLC
(CXCL13)
CA125
Cardiac Troponin I
(cTnI)
Cathepsin S
CEA
C-Peptide
Endothelin-1
Eotaxin-1
(CCL11)
GCSF
GDNF
GM-CSF
HGFR
HIV type-1 p24
  • Gene Symbol: gag-pol
  • Gene ID: 155348
  • Accession #: P04585
IFN-gamma
IL-1 alpha
(IL-1 F1)
IL-1 beta
(IL-1 F2)
IL-2
IL-3
IL-4
IL-5
IL-6
IL-7
IL-8
(CXCL8)
IL-10
IL-12 p70
IL-13
IL-15
IL-16
IL-17A
IL-22
IL-23a
IL-23
  • Gene Symbol: IL23A; IL12B
  • Gene ID: 51561; 3593
  • Accession #: P29460, Q9NPF7
IL-28A
(IFN-lambda 2)
IL-33
(IL-1 F11)
IP-10
(CXCL10)
Leptin
LIF
MAPT
(Tau)
MCP-1
(CCL2)
NAP-2
(PPBP/CXCL7)
NRG1-alpha
(HRG1-alpha)
NRG1-beta 1
PLGF
PSA-free
TGF alpha
TGF beta 1
TNF alpha
TNF beta
(TNFSF1B)
TRAIL
(TNFSF10)
Troponin I
     

Mouse Targets

GM-CSF
IL-1 beta
(IL-1 F2)
IL-10
IL-17A
IL-17F
IL-22
IL-23
  • Gene Symbol: Il23a; Il12b
  • Gene ID: 83430; 16160
  • Accession #: Q9EQ14, P43432
IL-6
TNF alpha
 


Rat Targets

IL-1 beta
(IL-1 F2)

View the Complete List of Biomarkers Available

To receive a quote*, fill out the sample service form linked below and email it to orders@raybiotech.com<.

*10 sample minimum

Sample Service FormSample Shipping Instructions

How It Works

Simoa is based upon the isolation of individual immunocomplexes on paramagnetic beads using standard ELISA reagents. The main difference between Simoa and conventional immunoassays lies in the ability to trap single molecules in femtoliter-sized wells, allowing for a “digital” readout of each individual bead to determine if it is bound to the target analyte or not.

Simoa Sensitivity Comparison

Representative Data

Ultrasensitive IL-6 assay

IL-6 Multiday Testing


 

Day 1

Day 2

Day 3

Mean

CV

Serum 1

2.8845

2.8332

2.7788

2.8322

1.9%

Serum 2

1.8079

1.8785

1.8792

1.8552

2.2%

Serum 3

2.2035

2.1724

2.2078

2.1946

0.9%

References