Rabbit Anti-Actin (ACTB/ACTC) (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P68032 |
| Gene Id | 70 |
| Gene Symbols | ACTC1 |
| Protein Name / Synonyms | Actin (ACTB/ACTC) (N-term) |
| Clonality | Polyclonal |
| Preparation | This Actin (ACTB/ACTC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human Actin (ACTB/ACTC). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cardiovascular Disease, Cytoskeletal Reorganization |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
Specificity
Predicted Reactivity
Rat, Zebrafish, Bovine, Chicken, Drosophila, C.Elegans, Hamster, Pig, Monkey, Rabbit, Xenopus, Yeast
Other Names
ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin
NCBI Accession #
NP_005150.1
Other Accession #
P60010; P68136; P68135; P68137; P68134; P68133; P68139; P68138; P63269; P63268; P63267; P63270; Q5E9B5; A2BDB0; P63259; P63260; P63261; Q5ZMQ2; P63258; P04751; P68035; P68033; P68034; Q3ZC07; O93400; P60711; P29751; Q6QAQ1; P60710; Q4R561; P60709; P48975;
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42019
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
 | Western blot analysis of ACTB/ACTC Antibody (N-term) in mouse testis tissue lysates (35ug/lane). Target protein (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ACTB/ACTC antibody (N-term) (Cat# 102-12723), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of Actin (ACTB/ACTC) Antibody (N-term)(Cat# 102-12723) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.