Rabbit Anti-Human CD8B (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P10966 |
| Gene Id | 926 |
| Gene Symbols | CD8B |
| Protein Name / Synonyms | CD8B (N-term) |
| Clonality | Polyclonal |
| Preparation | This CD8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CD8B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Specificity
Other Names
CD8B; CD8B1; T-cell surface glycoprotein CD8 beta chain; CD_antigen=CD8b; Flags: Precursor
NCBI Accession #
NP_001171571.1;NP_004922.1;NP_742099.1;NP_742100.1;NP_757362.1
Other Accession #
A6NJW9
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23722
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of anti-CD8B1 Pab (Cat# 102-12474) in K562 cell line lysates (35ug/lane). CD8B1(arrow) was detected using the purified Pab. |
 | Flow cytometric analysis of jurkat cells using CD8B Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.