Rabbit Anti-Human CDK2 (T14) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P24941 |
| Gene Id | 1017 |
| Gene Symbols | CDK2 |
| Protein Name / Synonyms | CDK2 (T14) |
| Clonality | Polyclonal |
| Preparation | This CDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK2. |
| Concentration (lot specific) | 0.290 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Hamster, Xenopus
Other Names
CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase
NCBI Accession #
NP_001789.2;NP_439892.2
Other Accession #
Q80YP0; Q00526; P23437; Q63699; P97377; O55076; Q5E9Y0
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
33930
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Cdk2 Antibody (T14) (Cat# 102-17402) western blot analysis in 293,Hela cell line lysates (35ug/lane).This demonstrates the hCdk2 antibody detected the hCdk2 protein (arrow). |
 | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK2 Antibody (T14) (Cat# 102-17402), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
