Rabbit Anti-DHCR24 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q15392 |
| Gene Id | 1718 |
| Gene Symbols | DHCR24 |
| Protein Name / Synonyms | DHCR24 (N-term) |
| Clonality | Polyclonal |
| Preparation | This DHCR24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids from the N-terminal region of human DHCR24. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Specificity
Predicted Reactivity
Monkey
Other Names
DHCR24; KIAA0018; Delta(24)-sterol reductase; 24-dehydrocholesterol reductase; 3-beta-hydroxysterol delta-24-reductase; Diminuto/dwarf1 homolog; Seladin-1
NCBI Accession #
NP_055577.1
Other Accession #
Q8VCH6; Q60HC5
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
60101
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-DHCR24 Antibody (N-term) (Cat#AP2851a) in HepG2 cell line lysates (35ug/lane). DHCR24 (arrow) was detected using the purified Pab. |
 | Western blot analysis of anti-DHCR24 Antibody (N-term) (Cat#AP2851a) in mouse liver tissue lysates (35ug/lane). DHCR24 (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.