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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9CWR8 |
| Gene Id | 54427 |
| Gene Symbols | DNMT3L |
| Protein Name / Synonyms | Dnmt3L |
| Clonality | Polyclonal |
| Preparation | This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Specificity
Predicted Reactivity
Rat
Other Names
Dnmt3l; DNA (cytosine-5)-methyltransferase 3-like
NCBI Accession #
NP_001075164.1;NP_062321.1
Other Accession #
Q1LZ50
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
47993
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of Mouse Dnmt3L Antibody (Cat# 102-10722) in Hela cell line lysates (35ug/lane). Dnmt3l (arrow) was detected using the purified Pab. |
 | Dnmt3l Antibody (C403) (Cat# 102-10722) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dnmt3l antibody detected the Dnmt3l protein (arrow). |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.