Rabbit Anti-Human ESX1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8N693 |
| Gene Id | 80712 |
| Gene Symbols | ESX1 |
| Protein Name / Synonyms | ESX1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This ESX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human ESX1. |
| Concentration (lot specific) | 0.280 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.
Specificity
Other Names
ESX1; ESX1L; ESX1R; Homeobox protein ESX1; Extraembryonic, spermatogenesis, homeobox 1; Homeobox protein ESX1-N; Homeobox protein ESX1-C
NCBI Accession #
NP_703149.1
Other Accession #
NP_703149.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44297
Recommended Dilutions
WB: 1:1000
 | ESX1 Antibody (N-term) (Cat# 102-13340) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ESX1 antibody detected the ESX1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.