CD279 is a 55 kD member of the immunoglobulin superfamily and contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region. CD279 plays a key role in peripheral tolerance and autoimmune disease and is expressed in activated T cells, B cells, and myeloid cells. The ligands of CD279 include PD-L1 and PD-L2, and there is evidence that these ligands have overlapping functions and expression in normal tissues.

Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.

Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.