Human Long-[arg3] Insulin like Growth Factor-1 (IGF-1), also called as IGF long R3 protein, mediates many of the growth-promoting effects of growth hormone. IGF1 also stimulates both proliferation and differentiation of myogenic precursor cells. In vivo IGFs are bound to one of the members of a family of six high-affinity IGF binding proteins (IGFBP 1-6) that regulate their biological activity. One of these binding proteins, IGFBP-3, affects cell proliferation via both IGF-dependent and IGF-independent mechanisms and it has generally been shown to suppress proliferation of cultured cells.

The Mouse anti-human IGF-1 antibody specifically detects targets derived from human recombinant protein at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity.

Store at 4^°C if intended for use within one month, otherwise, store at -20^°C to -80^°C. The lyophilizedantibody is stable for at least 18 months after the date of receipt when stored at -20^°C to -80^°C. After reconstitution, it can be aliquoted and stored frozen at -20^°C to -80^°C in a manual defrost freezer for 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4^°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.