Rabbit Anti-Human IL1R (C-term E487) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P14778 |
| Gene Id | 3554 |
| Gene Symbols | IL1R1 |
| Protein Name / Synonyms | IL1R (C-term E487) |
| Clonality | Polyclonal |
| Preparation | This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R. |
| Concentration (lot specific) | 0.368 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Specificity
Predicted Reactivity
Rat
Other Names
IL1R1; IL1R; IL1RA; IL1RT1; Interleukin-1 receptor type 1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; Interleukin-1 receptor type I; p80; CD_antigen=CD121a; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form
NCBI Accession #
NP_000868.1
Other Accession #
Q02955
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
65402
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-IL1R (Cat# 102-16757) in HL60 cell line lysates (35ug/lane). IL1R (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with IL1R antibody (C-term E487), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.