Rabbit Anti-Human IMPDH1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P20839 |
| Gene Id | 3614 |
| Gene Symbols | IMPDH1 |
| Protein Name / Synonyms | IMPDH1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1. |
| Concentration (lot specific) | 0.430 mg/ml |
| Recommended Applications | Western Blotting, IF, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
IMPDH1; IMPD1; Inosine-5'-monophosphate dehydrogenase 1; IMPDH-I
NCBI Accession #
NP_000874.2;NP_001096075.1;NP_001136045.1;NP_001136046.1;NP_001136047.1;NP_001136048.1;NP_899066.1
Other Accession #
D3ZLZ7; P50096; A0JNA3; NP_001136045.1; NP_001096075.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55406
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; IHC: 1:10-50
 | IMPDH1 Antibody (C-term) (Cat# 102-12053) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IMPDH1 antibody detected the IMPDH1 protein (arrow). |
 | Confocal immunofluorescent analysis of IMPDH1 Antibody (C-term) (Cat# 102-12053) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | IMPDH1 Antibody (C-term) (102-12053)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IMPDH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.